To use the mouse, simply plug in the nano receiver to a USB port and switch on the mouse. The nano receiver is also small enough for it to be plugged in once and left connected, so it is the perfect mouse to use when on the move or for use on the desktop with minimal fuss. To preserve battery power, the GO NANO Mouse has a sleep mode. After a short period of inactivity the mouse will enter sleep mode. Simply press any of the buttons to wake it up again.